Integrating microbes, genetics, and molecular biology to prevent cardiovascular disease
The Hypertension Research Laboratory
Research
Unlocking the Mysteries of Blood Pressure Regulation
Our vision is to find the molecular mechanisms behind blood pressure regulation. This is achieved using the latest technology, which includes detecting RNA molecules at the single-cell level using sequencing and imaging, developing new knockout models using CRISPR/Cas9 technology and sequencing gut microbes, all of that integrated with traditional techniques in the fields of physiology and cardiovascular imaging.
In an effort to gain a better understanding of the world around us, we have recently begun to use a new technique to investigate the organization and functionality of the diverse parts of our experimental model. We are currently looking to expand this work by collaborating with other labs who have the facilities and prior experience to investigate this project further.
With work previously done by a former lab member, we have developed a powerful tool for use in the identification and characterization of the processes in our model system. A major advantage of this development is its improved sensitivity, which allows it to detect subtle dynamic property changes in response to our experimentation.
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