Marques Laboratory

School of Biological Sciences

Do you want to learn more about our research? Check out our published work

You can check our latest papers on PubMed and Google Scholar


Coming soon! Lots of exciting papers being approved, under review and submitted at the moment. 


Marques FZ, Jama HA, Tsyganov K, Gill PA, Rhys-Jones D, Muralitharan RR, Muir J, Holmes A, Mackay CR. Guidelines for Transparency on Gut Microbiome Studies in Essential and Experimental Hypertension. Hypertension, 2019;74:1279–1293. [Read here]

Jackson KL, Head GA, Gueguen C, Stevenson ER, Lim JK, Marques FZ. Mechanisms responsible for Genetic Hypertension in Schlager BPH/2 Mice. Frontiers in Physiology, section Integrative Physiology. 2019;10: 1311 [Read here]

Beale AL, Kaye DM, Marques FZ. The role of the gut microbiome in sex differences in arterial pressure. Biology of Sex Differences. 2019; 10:22. [Read here]

Jama H, Beale AL, Shihata WA, Marques FZ. The effect of diet on hypertensive pathology: is there a link via gut microbiota-driven immune-metabolism. Cardiovascular Research. 2019; 115:1435-1447. [Read here]

Paim LR, Schreiber R, de Rossi G, Matos-Souza JR, Costa E Silva AA, Calegari DR, Cheng S, Marques FZ, Sposito AC, Gorla JI, Cliquet A Jr, Nadruz W Jr. Circulating microRNAs, Vascular Risk, and Physical Activity in Spinal Cord-Injured Subjects. J Neurotrauma. 2019;36:845-852. [Read here]

Jama H, Kaye DM, Marques FZ. The Gut Microbiota and Blood Pressure in Experimental Models. Current Opinion in Nephrology and Hypertension. 2019; 28:97-104. [Read here]

Gueguen C, Jackson KL, Marques FZ, Eikelis N, Phillips S, Stevenson ER, Charchar FJ, Lambert GW, Davern PJ, Head GA. Renal nerves contribute to hypertension in Schlager BPH/2J mice. Hypertension Research. 2019;42:306-318. [Read here]



Jama H, Kaye DM, Marques FZ. Population-Based Gut Microbiome Associations With Hypertension: The Need for More Detailed Phenotypes. Circulation Research. 2018;123:1185–1187. [Read here]

Marques FZ, Mackay CR, Kaye DM. Beyond gut feelings: how the gut microbiota regulates blood pressure. Nat Rev Cardiol. 2018 Jan;15(1):20-32. [Read here]

Marques FZ. Missing Heritability of Hypertension and Our Microbiome. Circulation. 2018 Oct 2;138(14):1381-1383. [Read here​]


Booth SA, Wadley GD, Marques FZ, Wlodek ME, Charchar FJ. Fetal growth restriction shortens cardiac telomere length but this is attenuated by exercise in early life. Physiol Genomics. 2018 Sep 7. [Epub ahead of print] [Read here]


Paim LR, Schreiber R, de Rossi G, Matos-Souza JR, Costa E Silva AA, Calegari DR, Cheng S, Marques FZ, Sposito AC, Gorla JI, Cliquet A Jr, Nadruz W Jr. Circulating microRNAs, Vascular Risk, and Physical Activity in Spinal Cord-Injured Subjects. J Neurotrauma. 2018 Sep 27. [Epub ahead of print] [Read here]


Wang Y, Lumbers ER, Arthurs AL, Corbisier de Meaultsart C, Mathe A, Avery-Kiejda KA, Roberts CT, Pipkin FB, Marques FZ, Morris BJ, Pringle KG. Regulation of the human placental (pro)renin receptor-prorenin-angiotensin system by microRNAs. Mol Hum Reprod. 2018 Sep 1;24(9):453-464. [Read here]


Marques FZ, Chu PY, Ziemann M, Kaspi A, Kiriazis H, Du XJ, El-Osta A, Kaye DM. Age-Related Differential Structural and Transcriptomic Responses in the Hypertensive Heart. Front Physiol. 2018 Jul 9;9:817. [Read here]


Prestes PR, Marques FZ, Lopez-Campos G, Lewandowski P, Delbridge LMD, Charchar FJ, Harrap SB. Involvement of human monogenic cardiomyopathy genes in experimental polygenic cardiac hypertrophy. Physiol Genomics. 2018 Sep 1;50(9):680-687. [Read here]


Eikelis N, Marques FZ, Hering D, Marusic P, Head GA, Walton AS, Lambert EA, Esler MD, Sari CI, Schlaich MP, Lambert GW. A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension. J Hypertens. 2018 Jul;36(7):1571-1577. [Read here]


Jackson KL, Marques FZ, Lim K, Davern PJ, Head GA. Circadian Differences in the Contribution of the Brain Renin-Angiotensin System in Genetically Hypertensive Mice. Front Physiol. 2018 Mar 19;9:231. [Read here]

Marques FZ, Nelson E, Chu PY, Horlock D, Fiedler A, Ziemann M, Tan JK, Kuruppu S, Rajapakse NW, El-Osta A, Mackay CR, Kaye DM. High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice. Circulation. 2017 Mar 7;135(10):964-977. [Read here]

Marques FZ, Eikelis N, Bayles RG, Lambert EA, Straznicky NE, Hering D, Esler MD, Head GA, Barton DA, Schlaich MP, Lambert GW. A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism. Mol Psychiatry. 2017 Jan;22(1):134-141. [Read here]

Giam B, Kuruppu S, Chu PY, Smith AI, Marques FZ, Fiedler A, Horlock D, Kiriazis H, Du XJ, Kaye DM, Rajapakse NW. N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy. Sci Rep. 2017 Dec 18;7(1):17718. [Read here]

Marques FZ, Prestes PR, Byars SG, Ritchie SC, Würtz P, Patel SK, Booth SA, Rana I, Minoda Y, Berzins SP, Curl CL, Bell JR, Wai B, Srivastava PM, Kangas AJ, Soininen P, Ruohonen S, Kähönen M, Lehtimäki T, Raitoharju E, Havulinna A, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, McGlynn M, Kelly J, Wlodek ME, Lewandowski PA, Delbridge LM, Burrell LM, Inouye M, Harrap SB, Charchar FJ. Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure. J Am Heart Assoc. 2017 Jun 14;6(6). pii: e005971. [Read here]


Stevenson ER, Johns EM, Marques FZ, Jackson KL, Davern PJ, Evans RG, Head GA. Positive allosteric modulation of GABAA receptors attenuates high blood pressure in Schlager hypertensive mice. J Hypertens. 2017 Mar;35(3):546-557. [Read here]


Denham J, Marques FZ, Bruns EL, O'Brien BJ, Charchar FJ. Epigenetic changes in leukocytes after 8 weeks of resistance exercise training. Eur J Appl Physiol. 2016 Jun;116(6):1245-53. [Read here]


Marques FZ, Vizi D, Khammy O, Mariani JA, Kaye DM. The transcardiac gradient of cardio-microRNAs in the failing heart. Eur J Heart Fail. 2016 Aug;18(8):1000-8. doi: 10.1002/ejhf.517. Epub 2016 Apr 12. PubMed PMID: 27072074. [Read here]

Prestes PR, Marques FZ, Lopez-Campos G, Booth SA, McGlynn M, Lewandowski P, Delbridge LM, Harrap SB, Charchar FJ. Tripartite motif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22. J Hypertens. 2016 May;34(5):950-8. [Read here]

Marques FZ, Booth SA, Prestes PR, Curl CL, Delbridge LM, Lewandowski P, Harrap SB, Charchar FJ. Telomere dynamics during aging in polygenic left ventricular hypertrophy. Physiol Genomics. 2016 Jan;48(1):42-9. [Read here]


Marques FZ, Charchar FJ. microRNAs in Essential Hypertension and Blood Pressure Regulation. Adv Exp Med Biol. 2015;888:215-35. [Read here]

Marques FZ, Romaine SP, Denniff M, Eales J, Dormer J, Garrelds IM, Wojnar L, Musialik K, Duda-Raszewska B, Kiszka B, Duda M, Morris BJ, Samani NJ, Danser AJ, Bogdanski P, Zukowska-Szczechowska E, Charchar FJ, Tomaszewski M. Signatures of miR-181a on the Renal Transcriptome and Blood Pressure. Mol Med. 2015 Nov;21(1):739-748. [Read here]

Veerabhadrappa P, Burger D, Brouwers S, Christofidou P, Bikai RE, Hannah-Shmouni F, Kruger R, Marques FZ, Rehman Mian MO, Montezano AC, Romero CA, Peña-Silva RA, Wainford RD, Charchar FJ, Schutte AE, Tomaszewski M. Across the globe in 4 months: two International Society of Hypertension new investigator symposia in 2014. J Hypertens. 2015 Apr;33(4):891-3. [Read here]

Denham J, O'Brien BJ, Marques FZ, Charchar FJ. Changes in the leukocyte methylome and its effect on cardiovascular-related genes after exercise. J Appl Physiol (1985). 2015 Feb 15;118(4):475-88. [Read here]

Marques FZ, Booth SA, Charchar FJ. The emerging role of non-coding RNA in essential hypertension and blood pressure regulation. J Hum Hypertens. 2015 Aug;29(8):459-67. [Read here]

For papers older than 2015 please check PubMed and Google Scholar